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Wayne State study links head, neck cancers to air pollution

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Monday, December 2, 2024   

Exposure to air pollution is a growing concern for public health and a breakthrough study from Wayne State University is shedding new light on its link to head and neck cancers.

In collaboration with Johns Hopkins University and Mass General Brigham, Wayne State researchers found fine particulate matter pollution known as PM2.5 may greatly increase the risk of cancers in the upper respiratory system. It is the tiny form of pollutants found in smoke, car exhaust and industrial emissions.

Dr. John Cramer, associate professor of otolaryngology at Wayne State University and the study's co-author, explained where the condition appears.

"Head and neck is actually very similar to lung cancer," Cramer explained. "These are cancers that typically occur in the lining of the mouth, the throat or the voice box."

According to the report, research on air pollution's effects on the lungs and heart is extensive but studies linking it to head and neck cancers are limited.

Dr. Cramer pointed out the tissue in the head and neck is especially vulnerable to air pollution because it comes into direct contact with the harmful particles. He emphasized there is a strong link between tobacco smoke and the most common type of head and neck cancer, squamous cell carcinoma.

How aggressive is it? Cramer stressed it is in the family of medium to highly aggressive cancers.

"Not the most aggressive cancer out there but it's also not one that is a total turtle of the cancer world," Cramer outlined. "I think it's a bit more of kind of a rabbit that can be a little bit sneaky and kind of get away."

He added the treatments for head and neck cancers, like radiation and surgery, are often intense and do not always succeed. He emphasized he would rather see fewer cases than treat them.

Disclosure: Wayne State University contributes to our fund for reporting on Civic Engagement, Education, Environment, and Health Issues. If you would like to help support news in the public interest, click here.


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