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Day two of David Pecker testimony wraps in NY Trump trial; Supreme Court hears arguments on Idaho's near-total abortion ban; ND sees a flurry of campaigning among Native candidates; and NH lags behind other states in restricting firearms at polling sites.

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The Senate moves forward with a foreign aid package. A North Carolina judge overturns an aged law penalizing released felons. And child protection groups call a Texas immigration policy traumatic for kids.

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Wyoming needs more educators who can teach kids trade skills, a proposal to open 40-thousand acres of an Ohio forest to fracking has environmental advocates alarmed and rural communities lure bicyclists with state-of-the-art bike trail systems.

Horses could hold key to treating injury-related arthritis

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Tuesday, February 13, 2024   

Researchers at Colorado State University are making headway in identifying how osteoarthritis progresses in horses, and their findings could one day also help people who develop the degenerative disease after injuring a knee, elbow or shoulder.

Lynn Pezzanite, doctor of veterinary medicine and assistant professor at Colorado State University, said the disease affects nearly eight in ten horses over age 15.

"It's the most common disorder affecting joints in horses, as well as in people, and one of the most common disorders that we treat overall in horses. It's one of the most common reasons horses present to a veterinarian," she said.

Pezzanite and her team are hoping to find markers of how osteoarthritis develops in horses by studying individual immune cells in joint fluid. Those markers may provide insights on how veterinarians can use gene therapies or other treatments at specific stages to slow the disease's progression.

Typically, people and animals only show signs of osteoarthritis at advanced stages, when they experience joint pain. Pezzanite believes information in immune cells might expose the disease much earlier, even before evidence appears on X-rays.

"Our goal with this work is to look at those very early stages in horses that have post-traumatic arthritis, so that we can determine that tipping point of when we should be intervening or not. And hopefully this will inform treatment in humans as well," she continued.

Pezzanite said people could benefit from this research if the immune markers can be translated across species. Physicians would have better information about when to intervene before full-blown osteoarthritis develops.

"If you're playing soccer and twist your knee, tear your ACL, we would potentially be able to take a sample of that joint fluid and know whether you're going to develop arthritis or not," she explained. "Which would allow us to be more aggressive in treatment of that joint."

Disclosure: Colorado State University contributes to our fund for reporting on Environment, Health Issues, Social Justice. If you would like to help support news in the public interest, click here.


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