By Jim Robbins for KFF Health News.
Broadcast version by Mike Moen for Minnesota News Connection reporting for the KFF Health News-Public News Service Collaboration

Each fall, millions of hunters across North America make their way into forests and grasslands to kill deer. Over the winter, people chow down on the venison steaks, sausage, and burgers made from the animals.

These hunters, however, are not just on the front lines of an American tradition. Infectious disease researchers say they are also on the front lines of what could be a serious threat to public health: chronic wasting disease.

The neurological disease, which is contagious, rapidly spreading, and always fatal, is caused by misfolded proteins called prions. It currently is known to infect only members of the cervid family — elk, deer, reindeer, caribou, and moose.

Animal disease scientists are alarmed about the rapid spread of CWD in deer. Recent research shows that the barrier to a spillover into humans is less formidable than previously believed and that the prions causing the disease may be evolving to become more able to infect humans.

A response to the threat is ramping up. In 2023, a coalition of researchers began “working on a major initiative, bringing together 68 different global experts on various aspects of CWD to really look at what are the challenges ahead should we see a spillover into humans and food production,” said Michael Osterholm, an expert in infectious disease at the University of Minnesota and a leading authority on CWD.

“The bottom-line message is we are quite unprepared,” Osterholm said. “If we saw a spillover right now, we would be in free fall. There are no contingency plans for what to do or how to follow up.”

The team of experts is planning for a potential outbreak, focusing on public health surveillance, lab capacity, prion disease diagnostics, surveillance of livestock and wildlife, risk communication, and education and outreach.

Despite the concern, tens of thousands of infected animals have been eaten by people in recent years, yet there have been no known human cases of the disease.

Many hunters have wrestled with how seriously to take the threat of CWD. “The predominant opinion I encounter is that no human being has gotten this disease,” said Steve Rinella, a writer and the founder of MeatEater, a media and lifestyle company focused on hunting and cooking wild game.

They think, “I am not going to worry about it because it hasn’t jumped the species barrier,” Rinella said. “That would change dramatically if a hunter got CWD.”

Other prion diseases, such as bovine spongiform encephalopathy, also known as mad cow disease, and Creutzfeldt-Jakob disease, have affected humans. Mad cow claimed the lives of more than 200 people, mostly in the United Kingdom and France. Some experts believe Parkinson’s and Alzheimer’s also may be caused by prions.

First discovered in Colorado in captive deer in 1967, CWD has since spread widely. It has been found in animals in at least 32 states, four Canadian provinces, and four other foreign countries. It was recently found for the first time in Yellowstone National Park.

Prions behave very differently than viruses and bacteria and are virtually impossible to eradicate. Matthew Dunfee, director of the Chronic Wasting Disease Alliance, said experts call it a “disease from outer space.”

Symptoms are gruesome. The brain deteriorates to a spongy consistency. Sometimes nicknamed “zombie deer disease,” the condition makes infected animals stumble, drool, and stare blankly before they die. There is no treatment or vaccine. And it is extremely difficult to eradicate, whether with disinfectants or with high heat — it even survives autoclaving, or medical sterilization.

Cooking doesn’t kill prions, said Osterholm. Unfortunately, he said, “cooking concentrates the prions. It makes it even more likely” people will consume them, he said.

Though CWD is not known to have passed to humans or domestic animals, experts are very concerned about both possibilities, which Osterholm’s group just received more than $1.5 million in funding to study. CWD can infect more parts of an animal’s body than other prion diseases like mad cow, which could make it more likely to spread to people who eat venison — if it can jump to humans.

Researchers estimate that between 7,000 and 15,000 infected animals are unknowingly consumed by hunter families annually, a number that increases every year as the disease spreads across the continent. While testing of wild game for CWD is available, it’s cumbersome and the tests are not widely used in many places.

A major problem with determining whether CWD has affected humans is that it has a long latency. People who consume prions may not contract the resulting disease until many years later — so, if someone fell sick, there might not be an apparent connection to having eaten deer.

Prions are extremely persistent in the environment. They can remain in the ground for many years and even be taken up by plants.

Because the most likely route for spillover is through people who eat venison, quick testing of deer and other cervid carcasses is where prevention is focused. Right now, a hunter may drive a deer to a check station and have a lymph node sample sent to a lab. It can be a week or more before results come in, so most hunters skip it.

Montana, for example, is famous for its deer hunting. CWD was first detected in the wild there in 2017 and now has spread across much of the state. Despite warnings and free testing, Montana wildlife officials have not seen much concern among hunters. “We have not seen a decrease in deer hunting because of this,” said Brian Wakeling, game management bureau chief for the Montana Department of Fish, Wildlife & Parks. In 2022 Montana hunters killed nearly 88,000 deer. Just 5,941 samples were taken, and 253 of those tested positive.

Experts believe a rapid test would greatly increase the number of animals tested and help prevent spillover.

Because of the importance of deer to Indigenous people, several tribal nations in Minnesota are working with experts at the University of Minnesota to come up with ways to monitor and manage the disease. “The threat and potential for the spread of CWD on any of our three reservations has the ability to negatively impact Ojibwe culture and traditions of deer hunting providing venison for our membership,” said Doug McArthur, a tribal biologist for the White Earth Nation, in a statement announcing the program. (The other groups referenced are the Leech Lake Band of Ojibwe and Red Lake Band of Chippewa.) “Tribes must be ready with a plan to manage and mitigate the effects of CWD … to ensure that the time-honored and culturally significant practice of harvesting deer is maintained for future generations.”

Peter Larsen is an assistant professor in the College of Veterinary Medicine at the University of Minnesota and co-director of the Minnesota Center for Prion Research and Outreach. The center was formed to study numerous aspects of prions as part of the push to get ahead of possible spillover. “Our mission is to learn everything we can about not just CWD but other prionlike diseases, including Parkinson’s and Alzheimer’s disease,” he said. “We are studying the biology and ecology” of the misfolded protein, he said. “How do prions move within the environment? How can we help mitigate risk and improve animal health and welfare?”

Part of that mission is new technology to make testing faster and easier. Researchers have developed a way for hunters to do their own testing, though it can take weeks for results. There’s hope for, within the next two years, a test that will reduce the wait time to three to four hours.

“With all the doom and gloom around CWD, we have real solutions that can help us fight this disease in new ways,” said Larsen. “There’s some optimism.”


Jim Robbins wrote this story for KFF Health News.

A new report on lung cancer by the American Lung Association showed Maryland has quite a bit of room to improve diagnoses and treatment but experts said the state has taken some big steps in tackling it.

The report showed almost 17% of Marylanders at high risk for lung cancer were screened, a little less than the national average. Maryland fared better in other metrics, including lower rates of adult smokers and people unable to access treatment.

Aleks Casper, Maryland director of advocacy for the American Lung Association, said to improve the state's standing, Marylanders at risk of lung cancer need to be screened at higher rates.

"If we can get people screened, our chances of impacting all the other metrics improve," Casper explained. "If we get people screened and we can find it early, then we can connect them to treatment and we can connect them to surgery, which impacts outcomes."

The report also noted Latinos in Maryland are the least likely group to be diagnosed early.

Casper pointed out certain policies in Maryland have removed barriers to diagnosis and treatment. Just this year, Maryland became one of 15 states to require insurance to cover biomarker testing, including for lung cancer. The National Cancer Institute described biomarker testing as using a sample of tissue, blood or other fluid to look for genes or chromosomes which could increase a person's likelihood of developing certain cancers, which Casper emphasized is critical.

"Being able to test and determine what the best type of treatment for that person's disease, that kind of really individualized care and giving people access to that, is really important," Casper added.

Those who want to find out if they're eligible to be screened for lung cancer can take a quick test at savedbythescan.org.


get more stories like this via email

By Kyla Russell for WISH-TV.
Broadcast version by Joe Ulery for Indiana News Service reporting for the WISH-TV-Free Press Indiana-Public News Service Collaboration

Walking pneumonia cases in central Indiana have seen a steep increase in recent weeks, local physicians say.

"But what we've seen this summer, starting in July and August, was an explosion in the number of cases," said Dr. John Christenson, associate medical director of infection prevention at Riley Hospital for Children. "Some require admissions to intensive care units. Children die, adults die .. sometimes it invades the brain and it can cause an infection there."

Walking pneumonia is generally considered less severe than pneumonia, but can have lasting impacts if not caught early on. The disease is caused by mycoplasma pneumoniae, which can damage the lining of the respiratory tract, according to the CDC.

It is spread through droplets released when someone coughs or sneezes.

"Symptoms can begin mildly with sore throat, cough, or chest pain," Christenson said.

About two million people are diagnosed with the disease each year. This year is different, though.

While it's common for young children and adolescents to be impacted, small children born during the Covid-19 lockdown are seeing a surge in cases.

The CDC said diagnoses in kids between two and four years old jumped from 1% to 7.2% over a six-month time span this year.

"We saw a rebound after Covid," Christenson said.

During lockdown, people were wearing masks, staying home, and were not at school and work.

"What happened was a lot of people who could acquire an infection around that time, didn't," Christenson said. "So, now they're all susceptible. You bring in a new germ or an old germ into an environment and it spreads like wildfire."

Several local schools have seen an increase in students, asking parents to be on the lookout for symptoms and to take their child to a physician if needed.

As holiday gatherings begin, Christenson is heeding a similar call, especially in severe cases.

"That's when you need to take them to their healthcare professional to have them seen, and in some cases, get X-rays," Christenson said.

Additionally, Christenson said it is important to make sure families are up-to-date on all vaccinations.


Kyla Russell wrote this article for WISH-TV.


get more stories like this via email

More than one in three children is now overweight or obese, according to new research published in the Lancet medical journal.

The study found while Kentucky and other southern states are forecast to continue seeing rising levels of childhood obesity, some other states, such as Utah, will experience even higher spikes.

Ben Chandler, CEO of the Foundation for a Healthy Kentucky, said the Commonwealth is struggling to address health care and quality of life for kids.

"I think we're 45th in being overweight," Chandler observed. "It leads to a shorter life expectancy. It leads to tremendous spikes in the odds of getting any number of diseases and it has a huge cost attributed to it. "

Almost half of teens and young adults now are either overweight or obese, compared with 29% in 1990. The number is expected to jump by between 31% and 50% for adolescents, and by 29% to 33% for kids ages 6-11.

Chandler argued the state should increase funding for physical activity programs in schools and address the persistent lack of access to healthy and affordable fresh food. He added the issue cannot be tackled solely through individual behavior changes.

"There are a lot of environmental factors that are involved here," Chandler pointed out. "There's a lot of money, quite frankly, being spent in advertising for things that are bad for you."

The study also found among U.S. adults, if the current pattern continues, more than 250 million people will be overweight or obese by 2050.