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Pentagon announces another boat strike amid heightened scrutiny; An End to Hepatitis B Shots for All Newborns; DeWine veto protects Ohio teens from extended work hours; Wisconsin seniors rally for dignity amid growing pressures; Rosa Parks' legacy fuels 381 days of civic action in AL and the U.S.

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Trump escalates rhetoric toward Somali Americans as his administration tightens immigration vetting, while Ohio blocks expanded child labor hours and seniors face a Sunday deadline to review Medicare coverage.

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Native American tribes are left out of a new federal Rural Health Transformation Program, cold temperatures are burdening rural residents with higher energy prices and Missouri archivists says documenting queer history in rural communities is critical amid ongoing attacks on LGBTQ+ rights.

MD scientists create Latino genetic database for medical research

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Monday, November 4, 2024   

Genetic studies overwhelmingly are based on data from people of European descent. But University of Maryland, Baltimore scientists are working to change that.

Researchers have developed the Genetics of Latin American Diversity database, pulling information from more than 200 genetic studies on almost 54,000 people of Hispanic and Latin descent.

Timothy O'Connor, associate professor at the University of Maryland at Baltimore School of Medicine Institute for Genome Sciences, said the diversity is important because 95% of participants in genetic studies come from northwestern Europe.

"What ends up happening as a result of that is, we have a restricted view of genetic variation that we see in the world," said O'Connor. "Because of that, we miss out on genetic variation that might be causing a disease in one population, but not in another population."

Even though Latino representation makes up less than 1% of genetic data, O'Connor added that the number of people in datasets is exploding.

He said that made it possible to gather so much genetic data on this population.

The University of Maryland database should save other researchers time and money they'd be using to collect this information on their own.

O'Connor said he believes the creation of this database moves past large categorizations in ancestry that are largely based on race.

"What this allows us to do is to say, 'No these are distant cousins. These are people that are closely related at a much more fine scale,'" said O'Connor. "It moves us from this thinking about groups as kind of separate, into starting to think of everybody as kind of a continuous ancestry."

The Census Bureau says more than 19% of Americans identify as Latino, including more than 12% of Marylanders.




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